Foundational Platforms

Training, Mentoring, and Early Career Development

The Training, Mentoring, and Early Career Development platform will establish a sustainable training program to support emerging researchers and build capacity for research related to venous thromboembolism. Our training program aims to address unmet training needs, facilitate early career launch for junior scientists, and will be delivered according to best practices by training new and existing mentors. We will focus on developing clinician investigators and clinician scientists.

The Team

Platform Co-Leads

Marc Carrier (Ottawa, ON)
Sudeep Shivakumar (Halifax, NS)

Trainee Council

Chair: Rick Ikesaka - 2017-2018
Chair: Deborah Siegal - 2016-2017

This council is trainee-led and participation is open to all trainees involved in CanVECTOR activities. The council provides an opportunity for collaboration and cooperation amongst trainees and allows them to communicate their needs, concerns and feedback to CanVECTOR’s Scientific Steering Committee.

Trainee Award Committee

The role of the CanVECTOR Trainee Award Committee is to make decisions about the allocation of CanVECTOR training funds to trainee applicants.

Responsibilities of the CanVECTOR Trainee Award Committee include:

  • Develop the process and criteria for awarding training funds
  • Consider the availability of funding, including partner funding at academic institutions, when making decisions about awards
  • Endeavour to equitably award funding across CanVECTOR training sites, taking into consideration the applicant’s preferences, the training capacity at CanVECTOR sites, and the ability of the site to meet the applicant’s training needs
  • Review applications and recommend candidates for funding

Committee Co-chairs

  • Marc Carrier (Ottawa)
  • Sudeep Shivakumar (Halifax)

Committee Members

  • Shannon Bates (Hamilton)
  • Susan Kahn (Montreal)
  • Alejandro Lazo-Langner (London)
  • Agnes Lee (Vancouver)
  • Rita Selby (Toronto)
  • Vicky Tagalakis (Montreal)
  • Deborah Siegal (Hamilton)
  • Ed Conway (Vancouver)
  • Leslie Skeith (Calgary)

Ex-officio Member

  • Marc Rodger (CanVECTOR director)

Manager of the Training and Mentoring Platform

  • Nicole Langlois

CanVECTOR-funded Trainees 2015-2016

 

Thrombosis Canada CanVECTOR Research Fellowship

Leslie Skeith

Leslie Skeith (University of Ottawa; supervisor: Dr. Gonsalves)

Dr. Skeith completed her Internal Medicine residency at Western University and her Hematology residency at the University of Calgary. She is currently in a Thrombosis/Medical Education fellowship at the University of Ottawa and is completing a Master of Health Professions Education at the University of Illinois at Chicago (UIC). Her medical education research focus is in clinical decision-making and competency-based assessment for sub-specialty training, and her clinical research interest is in thrombosis/haemostasis and pregnancy.

CanVECTOR-funded Trainees 2016-2017

 

CanVECTOR Fellowship Award Recipients

Jameel Abdulrehman (University of Toronto; supervisor: Dr. Selby)

Dr. Abdulrehman completed his residency in Internal Medicine at Western University, and his residency in Adult Hematology at the University of Alberta. He is currently pursuing a clinical fellowship in Thrombosis and Hemostasis at the University of Toronto and a Masters in Clinical Epidemiology at McMaster University. Dr. Abdulrehman’s CanVECTOR project aims to investigate the use of rivaroxaban in individuals of weight >120kg.

 

 

Rick Ikesaka (University of Ottawa; supervisor: Dr. Carrier)

Dr. Ikesaka has completed both his Internal Medicine residency and hematology residency, both at the University of Ottawa, Dept. of Medicine. He is currently completing his Master of Science in Epidemiology and Thrombosis clinical fellowship. Dr. Ikesaka CanVECTOR project objective is to compare primary thromboprophylaxis with rivaroxaban in patients with malignancy and central venous catheters. Rick plans to complete a pilot studies to prove the viability, safety and efficacy of this prophylaxis strategy.

 

Adi Klil-Drori (McGill University; supervisor: Dr. Tagalakis)

Dr. Klil-Drori completed his Internal Medicine boards and Hematology boards in Israel, in 2011 and 2013 respectively.  He is currently completing a clinical epidemiology, Master of Science at Hebrew University, Jerusalem, Israel and will complete his Postdoctoral research fellowship at the Centre for Clinical Epidemiology, Jewish General Hospital and McGill University this year. He is also starting a 2-year clinical fellowship in early drug development in medical oncology.

Dr. Klil-Drori CanVECTOR project includes using population-based administrative databases to capture outpatient management of PE across Québec, Alberta and Ontario.  A few of his database analysis objectives include; review of the changes of clinical outcomes in outpatient management of PE from the pre-DOAC era (2000-2009); compare outcomes of outpatient and inpatient management of PE in a subset of low-risk PE patients in the pre-DOAC era, and to examine whether market entry of DOAC for the treatment of PE has affected the practice of outpatient management of PE.

 

Leslie Skeith

Leslie Skeith (University of Ottawa; supervisor: Dr. Gonsalves)

Dr. Skeith completed her Internal Medicine residency at Western University and her Hematology residency at the University of Calgary. She is currently in a Thrombosis/Medical Education fellowship at the University of Ottawa and is completing a Master of Health Professions Education at the University of Illinois at Chicago (UIC). Her medical education research focus is in clinical decision-making and competency-based assessment for sub-specialty training, and her clinical research interest is in thrombosis/haemostasis and pregnancy.

 

Thrombosis Canada CanVECTOR Research Fellowship

Mihir D. Bhatt (McMaster University; supervisor: Dr. Anthony Chan)

Dr. Bhatt completed his undergraduate degree in Bachelor of Health Sciences, followed by MD, residency in Pediatrics and fellowship in Pediatric Hematology/Oncology all at McMaster University. Dr. Bhatt is an active researcher with a special interest in pediatric hemostasis and thrombosis.

Dr. Bhatt Thrombosis Canada/ CanVECTOR project includes assessing the feasibility and safety of a multicenter trial administering weight adjusted FiXEd dose of low molecular weight heparin (Enoxaparin) to neonates with Thrombosis (FiXET Study). 

CanVECTOR Travel Awards

Adi Klil-Drori (McGill University)
Leslie Skeith (University of Ottawa)

CanVECTOR Research Start-up Awards

Rick Ikesaka (University of Ottawa; supervisor: Dr. Carrier)
Nicholas Meti (McGill University; supervisor: Dr. Tagalakis)
Mansoor Radwi (McMaster University; supervisor: Dr. Schulman)
Dwip Prajapati (University of Calgary; supervisor:Dr. Lang)

CanVECTOR-funded Trainees 2017-2018

 

CanVECTOR Fellowship Award Recipients

Adi Klil-Drori (McGill University; supervisor: Dr. Tagalakis)

Dr. Klil-Drori completed his Internal Medicine boards and Hematology boards in Israel, in 2011 and 2013 respectively.  He is currently completing a clinical epidemiology, Master of Science at Hebrew University, Jerusalem, Israel and will complete his Postdoctoral research fellowship at the Centre for Clinical Epidemiology, Jewish General Hospital and McGill University this year. He is also starting a 2-year clinical fellowship in early drug development in medical oncology.

Dr. Klil-Drori CanVECTOR project includes using population-based administrative databases to capture outpatient management of PE across Québec, Alberta and Ontario.  A few of his database analysis objectives include; review of the changes of clinical outcomes in outpatient management of PE from the pre-DOAC era (2000-2009); compare outcomes of outpatient and inpatient management of PE in a subset of low-risk PE patients in the pre-DOAC era, and to examine whether market entry of DOAC for the treatment of PE has affected the practice of outpatient management of PE.

 

Jameel Abdulrehman (University of Toronto; supervisor: Dr. Selby)

Dr. Abdulrehman completed his residency in Internal Medicine at Western University, and his residency in Adult Hematology at the University of Alberta. He is currently pursuing a clinical fellowship in Thrombosis and Hemostasis at the University of Toronto and a Masters in Clinical Epidemiology at McMaster University. Dr. Abdulrehman’s CanVECTOR project aims to investigate the use of rivaroxaban in individuals of weight >120kg.

 

Fatimah Al-Ani (The University of Western Ontario; supervisor: Dr. Lazo-Langner)

Dr. Fatimah Al-Ani obtained her medical degree from Baghdad, Iraq. She completed her training in Internal Medicine and in Hematology in Dubai, United Arab Emirates. Dr. Al-Ani obtained her Post Graduate Degree of Internal Medicine from the Royal College of Physicians of United Kingdom (MRCP of UK) in 2011. Upon moving to Canada, she joined Western University and completed a 3-year Research Fellowship in Hematology. Currently, she is pursuing a clinical fellowship in Adult Thrombosis Medicine at Western University. Dr. Al-Ani’s CanVECTOR project aims to develop a clinical prediction rule for the risk of venous thromboembolism in patients with acute leukemia. Her research interests are in Thromboembolism, population based studies, and systematic reviews. Her other ongoing projects include Validation of diagnostic algorithms for Venous Thromboembolism Using Linked Health Care Databases, and a systematic review of the efficacy and safety of DOACS in population based studies.

 

Rick Ikesaka (University of Ottawa; supervisor: Dr. Carrier)

Dr. Ikesaka has completed both his Internal Medicine residency and hematology residency, both at the University of Ottawa, Dept. of Medicine. He is currently completing his Master of Science in Epidemiology and Thrombosis clinical fellowship. Dr. Ikesaka CanVECTOR project objective is to compare primary thromboprophylaxis with rivaroxaban in patients with malignancy and central venous catheters. Rick plans to complete a pilot studies to prove the viability, safety and efficacy of this prophylaxis strategy.

 

Siavash Piran (McMaster University; supervisor: Dr. Schulman)

Dr. Siavash Piran graduated from University of Ottawa medical school in 2011. He completed his residency training in Internal Medicine at University of Ottawa and Hematology at McMaster University. 

He holds a Masters of Science degree in Laboratory Medicine and Pathobiology from the University of Toronto and is currently completing a Masters of Science degree in Health Research Methodology at McMaster University. Dr. Piran is currently a Clinical Scholar in the Division of Hematology and Thromboembolism at McMaster University. His CanVECTOR project is a pilot study on thromboprophylaxis for patients with spinal cord injury comparing low-molecular-weight heparin with apixaban.

CanVECTOR Studentship Award Recipients

Hasam Madarati (McMaster University; supervisor: Dr. Kretz)

 

Kanwal Singh (McMaster University; supervisor: Dr. Kretz) 

Kanwal is currently pursuing a Master’s degree in the Medical Sciences Program at McMaster University. He is interested in understanding the biochemistry and physiology of blood coagulation proteases. His CanVECTOR project investigates the regulation of the metalloprotease ADAMTS13, which controls the platelet-capturing activity of von Willebrand factor. Because von Willebrand factor is known to play a crucial role in the initiation phase of blood coagulation, improving our understanding ADAMTS13 may yield important insights into pathophysiology of VTE and other thrombotic disorders. His long term goal is to translate the unique properties of ADAMTS13 to other proteases in the cardiovascular system, which may have broad clinical impact on protease replacement therapy.

The Heart and Stroke  Foundation (HSF) Emerging Research Leaders Initiative (ERLI) Award 

Deborah Siegal (McMaster University; supervisor: Dr. Crowther)

Dr. Siegal graduated from Queen’s University School of Medicine in 2009. She completed Internal Medicine and Hematology training at McMaster University. She holds a Master of Science degree in Pharmacology from the University of Toronto and is completing a Master of Science degree in Health Research Methodology at McMaster University. Dr. Siegal is currently a Clinical Scholar in the Division of Hematology and Thromboembolism at McMaster University. She received a Thrombosis Canada Research Fellowship Award in 2014 and a Canadian Institutes of Health Research Fellowship Award in 2015, and has published 30 articles in peer-reviewed journals. Dr. Siegal’s primary research interest is iatrogenic bleeding complications. She has published scientific articles in prominent journals including The New England Journal of Medicine, Circulation, Blood and Journal of Thrombosis and Haemostasis on the topic of anticoagulant-associated bleeding and reversal. 

CanVECTOR Travel Award  

Siavash Piran (McMaster University)
Faizan Khan (University of Ottawa)

CanVECTOR Research Start-up Award 

Hasam Madarati (supervisor Dr. Kretz)
Salma Shivji (supervisor Dr. Suryanarayan)
Yan Xu  (supervisor(s) Dr. Wells / Dr. Sholzberg)
Rachelle Blackman (supervisor Dr. Shivakumar)
Leslie Skeith (supervisor Dr. Le Gal)

CanVECTOR CAEP Research Award 

Kerstin de Wit
Eddy Lang
Sameer Sharif

CanVECTOR Anticoagulation Forum Travel Award

Yan Xu

 

The Projects

1. Establish a Formal VTE Research Training Curriculum

A research training curriculum will be created with input from the Network membership, including trainees and young investigators. This new curriculum will be implemented at the existing thrombosis research training sites in Canada and will be available to other centres that plan to establish themselves as a new training site.

A CanVECTOR Fellow is taking the lead in the first stage of this initiative. Dr. Leslie Skeith has conducted a needs assessment to identify gaps and priority areas that should be addressed in a VTE research training curriculum.

Curriculum Working Group

Shannon Bates (McMaster)
Carol Gonsalves (Ottawa)
Agnes Lee (UBC)
Rita Selby (U of T)
Deborah Siegal (McMaster)
Leslie Skeith (Fellow in Ottawa)

2. Develop a Network-specific Academic Mentorship Program

Mentorship is beneficial at each training and career stage and has been shown to increase productivity, career retention and academic promotion in clinician-investigators/scientists. Mentorship is vital for securing research support in a discipline where grant funding is highly competitive, and essential to enable trainees to understand investigator responsibilities in an increasingly complex regulatory environment.

The objective of our mentoring program is to create a formal multi-site, multi-discipline mentoring program to ensure that mentorship is provided according to best practices to trainees, early career and more established investigators. To develop CanVECTOR’s academic mentorship program a plenary workshop was held on June 9th, 2016, led by Dr. Mamta Gautam, through the Canadian Medical Association’s Physician Leadership Institute. This interactive workshop allowed network members to actively participate in building our mentorship program.

3. Provide Support for Junior Faculty Research

Early career success barriers include inadequate access to salary support, protected time and space/equipment, but more importantly, a lack of adequate start-up operating funds for research. We have partnered with the Heart and Stroke Foundation to be able to provide research operating funds to new investigators through the Emerging Research Leaders Initiative (ERLI). This program is focused on supporting the successful early career launch of new investigators. The goal is for new investigators to establish an independent research program and allow them to demonstrate the research productivity that will allow them to successfully secure funding from major research granting agencies.

The Heart & Stroke Foundation has announced the third round of cardiovascular and cerebrovascular disease (CCVD) research ERLI grantees. Deborah Siegal, a CanVECTOR early career investigator at McMaster University, was selected as a recipient of the 2017-2018 ERLI award.  Her study titled Improving cardiovascular outcomes through safe resumption of anticoagulants after anticoagulant-related bleeding aims to find out when blood thinners can safely be restarted after bleeding to prevent blood clots and death.

For more information about the Emerging Research Leaders Initiative Competition and results, please visit: http://hsf.ca/research/en/emerging-research-leaders-initiative-competition-results-20172018

To learn more about Deborah Siegal's project Profile, please visit http://hsf.ca/research/sites/default/files/Siegal%2C%20D%20-%20ERLI%20Lay%20Summary.pdf