Pilot Trials Competitions

Background

The purpose of the Pilot Trials Competition funding opportunity is to build research capacity related to VTE and to enable CanVECTOR scientists to collect pilot data that will inform the conduct of larger multicentre clinical trials and increase the ability to attract external peer-reviewed funding.

The Pilot Trials Competition is an annual funding competition, typically held in the Spring, administered by the network's Clinical Trials & Shared Platforms.

Funding Details

A total of $100,000, dependent upon partnership funding, is available to fund one or more pilot studies. Funding for individual projects may be awarded over one or two years.

It is expected that the applicants will seek peer-reviewed funding for the full trial within 3 years of receiving CanVECTOR funds.

Eligibility

Applicants

  • The project team for the pilot study will include an investigator triad (senior investigator, an early or mid-career investigator, and a thrombosis fellow or trainee).  It is also expected that a methods expert will be included on the team.
  • At least one of the investigators in the triad must be a CanVECTOR member. 
  • Any investigator in the triad can be the lead investigator for the application. 
  • Inclusion of investigators from less-established research sites is encouraged.
  • CanVECTOR is committed to conducting research that is meaningful to patients and their families and to including trained patient partners on project teams. Applications should include a patient engagement strategy and/or patient partner. To request assistance, please contact the co-leads of the Patient Partners Platform, Dr. Lisa Duffett or Carol West, at info@canvector.ca. 

Projects

  • The project is expected to collect pilot data at two or more sites to inform a randomized controlled trial (RCT) that will be conducted at multiple CanVECTOR sites. Though it is often considered preferable, it is not an absolute requirement for the pilot study to have an RCT design; for example, it can be a cohort study that’s collecting pilot data that is needed to design a full RCT.
  • The pilot project must be completed within two years.
  • The research focus is to be related to prevention, diagnosis, or treatment of venous thromboembolism or its sequelae.
  • Applicants are encouraged to refer to the following online resources (open access) that outline methodology and best practices for pilot studies

    CONSORT 2010 statement: extension to randomised pilot and feasibility trials

    http://www.consort-statement.org/extensions/overview/pilotandfeasibility

    A tutorial on pilot studies: the what, why and how

    http://bmcmedresmethodol.biomedcentral.com/articles/10.1186/1471-2288-10-1

2021 Call for Proposals

Details about the next call for proposals will be announced in Spring 2021. Stay tuned for more details.